CJC-1295 w/DAC

V251230-9-00

Price range: $85.00 through $663.00

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Research Use Only

All products are intended solely for laboratory research and are not for human or animal consumption. By purchasing, the buyer agrees to use these products in compliance with all applicable laws.

Certificate of Analysis

Third-party tested for 99% purity, ID, quantity.

Certificate of Analysis

Third-party tested for endotoxins

CJC-1295 w/DAC Overview

CJC-1295 With DAC (Drug Affinity Complex) is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH) composed of 30 amino acids. The incorporation of the Drug Affinity Complex (DAC) allows the peptide to bioconjugate with endogenous albumin following administration. Since its development in the early 2000s, CJC-1295 With DAC has been studied extensively in controlled experimental settings for its extended plasma half-life and its continuous stimulation of pituitary somatotrophs to investigate growth hormone pathway dynamics. https://pubchem.ncbi.nlm.nih.gov/compound/CJC-1295-with-DAC

History

The peptide was originally engineered by Canadian biotechnology researchers looking to overcome the rapid enzymatic degradation that limits native GHRH (which breaks down in minutes). By adding a reactive maleimide group attached via a linker (the DAC technology), scientists successfully extended the peptide’s active experimental window to several days. Early experiments focused on its ability to maintain stable, elevated plasma levels of growth factors without the peak-and-trough spikes typical of shorter-lived secretagogues. Over time, studies broadened into systemic tissue repair, cellular regeneration, and metabolic adaptation models. _CJC-1295_a_Long-Acting_Anal

CJC-1295 w/DAC Structure

CAS #: V251230-9-00
Molecular Formula: C?????????H?????????N??????O?????? (Base peptide sequence before albumin conjuga

Research Findings

CJC-1295 With DAC has been studied in systemic, metabolic, structural, and physiological regeneration models, with reports of activity in continuous growth hormone pathway activation, insulin-like growth factor 1 (IGF-1) expression tracking, and cellular proliferation. Research also highlights its roles in supporting long-term signaling stability in preclinical systems without downregulating pituitary receptor responsiveness.

Key Areas of Research:

Systemic: Sustained growth hormone axis modulation, plasma half-life kinetics, receptor binding dynamics
Metabolic: Adipocyte lipid metabolism tracking, nitrogen retention balance, lean mass maintenance pathways
Structural: Extracellular matrix reinforcement, cellular protein synthesis upregulation, tissue repair acceleration
Physiological: Slow-wave deep sleep signaling trends, systemic vitality tracking, age-related physiological decline models

Together, these findings suggest broad experimental utility for CJC-1295 With DAC across multiple complex endocrine pathways. Its activity in systemic, metabolic, structural, and physiological models provides a robust foundation for exploring diverse aspects of sustained secretagogue signaling. By influencing processes such as cellular protein synthesis, growth factor expression, and metabolic regulation, CJC-1295 With DAC offers a highly stable and versatile platform for research into pathway longevity and systemic cellular resilience within experimental settings.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785721/

References

https://pubmed.ncbi.nlm.nih.gov/16330467/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785721/

Our Process

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

STEP 1

Precision Lyophilization

Manufactured in a controlled U.S. facility under strict compounding standards.

STEP 2

Verified Purity

Every batch third-party tested with HPLC and mass spectrometry.

STEP 3

Same-Day Fulfillment

Orders dispatched same-day from our
U.S. facility.

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Frequently Asked Questions

Everything you need to know about our products and processes.

What's the actual amount in each vial?

Each vial contains exactly what’s shown on the label. For example, a 10mg vial has exactly 10mg of lyophilized peptide. Researchers can divide it into smaller portions—like four 2.5mg measurements—but the total amount remains 10mg.

Are additional supplies needed?

Peptides are supplied as lyophilized powder. They do not come reconstituted, and any extra supplies must be sourced separately for research applications.

How long does a vial last?

In lyophilized powder form, peptides stay stable for up to 2 years. After reconstitution, it should be refrigerated and is generally stable for up to 2 months.

Does the product come with instructions?

Products from us do not include usage instructions, as they are strictly for in vitro research and prohibited by law for human or animal use. Misuse or unlawful application will result in permanent denial of service.

How should I store these products?

Lyophilized peptides should be stored away from heat and light. Once reconstituted, they must be refrigerated to maintain stability and efficacy.